David Sept

Prof. David Sept, Professor and Associate Chair of Biomedical Engineering, is a PI and Co-Director of the Michigan IRACDA program.  He is an established investigator in the area of computational biophysics with a primary interest in the dynamics and organization of the cytoskeleton and systems biology.


Prof. Susan V. Brooks is Professor of Molecular and Integrative Physiology and Biomedical Engineering. Dr. Brooks’ research is focused on age-associated declines in skeletal muscle and tendon structure and function. Specific interests include the causative role of oxidative stress in age-associated skeletal muscle atrophy and the impact that changes in muscle and tendon extracellular matrix  have on muscle function and susceptibility to injury.

Program Mentors

Prof. Daniel A. Beard is Professor in Molecular and Integrative Physiology and holds joint appointments in the departments of Biomedical Engineering, Internal Medicine and Emergency Medicine. His laboratory is focused on systems engineering approaches to understanding the biophysical and biochemical operation of physiological systems.

Prof. Eleanor J. “Josie” Clowney is an Assistant Professor of Molecular, Cellular and Developmental Biology. The Clowney lab investigates developmental and regulatory mechanisms that generate neural circuits and govern their function, using the olfactory system of the fruit fly Drosophila melanogaster as a model.

Prof. Katherine Gallagher
is the John R Pfeifer Collegiate Professor of Surgery and Associate Professor of Surgery and of Microbiology & Immunology. Her research is focused on histone methylation changes in bone marrow progenitor cells and the impact on peripheral macrophage phenotypes as it relates to wound healing and inflammation.


Prof. Malcolm J. Low is the David F. Bohr Collegiate Professor of Physiology in the Departments of Molecular & Integrative Physiology and Internal Medicine. His research focuses on the neural circuitry in the hypothalamus that regulates energy balance and glucose homeostasis and utilizes a combination of molecular, neuroanatomic and behavioral analyses in mutant mouse models of obesity and diabetes.

Prof. Carey Lumeng is the Frederick G L Huetwell Professor for the Cure and Prevention of Birth Defectsan and an Associate Professor of Pediatrics and of Molecular & Integrative Physiology. His lab is focused on understanding the function of leukocytes in adipose tissue and the mechanisms by which they are actived obesity and contribute to diabetes.

Prof. Geoffrey G. Murphy is Associate Director of the Neuroscience Graduate Program, a Research Professor for  the Molecular & Behavioral Neuroscience Institute and Professor of Molecular and Integrative Physiology His lab’s focus  is investigating how ion channels regulate neuronal function and complex behaviors such as learning & memory.


Prof. Santiago Schnell is a Professor of Molecular & Integrative Physiology and Computational Medicine & Bioinformatics.  He uses mathematical and computational models to investigate physiological systems comprising many interacting components to identify key mechanisms underlying the behavior of the system as a whole.   

David Sept

Prof. David Sept is a program Co-Director and a Professor of Biomedical Engineering and the Center for Computational Medicine and Bioinformatics.  His lab works on computational biophysics with a primary interest in the dynamics and organization of the cytoskeleton and systems biology.


Prof. Yatrik Shah is an Associate Professor in Molecular & Integrative Physiology and Internal Medicine.  He utilizes several novel mouse models that he has developed to accurately study the role of oxygen sensitive transcription factors in the liver and intestine.


Prof. Lonnie D. Shea is Professor and chair of Biomedical Engineering with joint appointment in Chemical Engineering.  His research is described as systems tissue engineering, which lies at the interface of regenerative medicine, systems biology and immune tolerance.

Prof. Joel Swanson is a Professor of Microbiology & Immunology.  His laboratory studies macrophage biology and for elucidating how microbes cause disease, with a focus on the macrophage’s ability to internalize fluids and particles by endocytosis, which includes the processes of phagocytosis, receptor-mediated endocytosis and macropinocytosis.

Professor Nils G. Walter is the Francis S Collins Collegiate Professor of Chemistry, Biophysics and Biological Chemistry.  His lab uses tools from chemical biology, analytical chemistry, biophysics, biochemistry, molecular biology, cell biology, and bioinformatics studying RNA biology and DNA nanotechnology, including the structure, dynamics and function of RNAs and DNA nanodevices outside and inside human cells.

Other Supporting Faculty

The faculty members below have expressed an interest in being a part of this program and perhaps mentoring a post-doctoral fellow appointed to the program.  After reviewing an applicants qualifications and experience, the review panel may suggest other University of Michigan faculty members, and the prospective appointee may request consideration by any qualified faculty mentor.  During the interview process prior to selection, the applicant will meet with several faculty members in order to  find the most suitable mentor.


Prof. James A. Ashton-Miller is the Albert Schultz Collegiate Research Professor with appointments in Mechanical Engineering, Biomedical Engineering, Internal Medicine and Kinesiology.  He uses computer simulations validated by experimental approaches to study the pathomechanics of unintentional injuries.


Prof. Tim Bruns is an Assistant Professor of Biomedical Engineering. Dr. Bruns runs the Peripheral Neural Engineering and Urodynamics lab, with a primary research focus of interfacing with the peripheral nervous system to control function and examine systems-level neurophysiology.


Prof. Cindy Chestek is an Assistant Professor of Biomedical Engineering. Her lab’s work focuses on brain machine interface systems, the ultimate goal being to develop clinically viable systems for control of prosthetic limbs.


Prof. Rhima Coleman is an Assistant Professor of Biomedical Engineering. She works in the area of tissue engineering and biomechanics, her primary focus being cartilage tissue regeneration through genetic reprogramming of cells.


Prof. Carol Elias is an Associate Professor of Molecular and Integrative Physiology with joint appointment in Obstetrics and Gynecology.  Her studies are focused on deciphering the mechanisms by which metabolic imbalance disrupts the reproductive neuroendocrine axis using genetically modified mouse models, systems neuroscience and molecular tools.


Prof. Lola Eniola-Adefeso is an Associate Professor in Biomedical and Chemical Engineering. She has expertise in blood flow dynamics, cell adhesion mechanisms, vascular targeting and the fabrication of drug delivery systems.


Prof. Xudong Fan is a Professor in the Biomedical Engineering Department.  His research focuses on the development and application of photonic bio/chemical sensors, micro/nano-fluidics, and nano-photonics for disease diagnostics and bio/chemical molecular analysis in liquid and gas phases.



Prof. Alberto Figueroa is the Edward B. Diethrich Associate Professor of Surgery and Associate Professor of Biomedical Engineering.  His research is focused on the areas of surgical planning, disease research and medical device design and evaluation.


Prof. Joan Greve is an Assistant Professor of Biomedical Engineering.  Prof. Greve is an expert in magnetic resonance imaging, her lab uses MRI and multi-modal imaging technique to study abdominal aortic aneurysms and other disease systems.


Prof. Ken Inoki is an Assistant Professor in Molecular & Integrative Physiology and a Research Assistant Professor at the Life Sciences Institute.  By using biochemical and genetic approaches, his research looks at the mechanisms and pathophysiological roles of nutrient-sensing signaling pathways in cell growth control and their implication in diabetes, aging and cancer.


Prof. David Kohn is a Professor with appointments in Biologic and Materials Sciences (Dentistry) and Biomedical Engineering.  His laboratory focuses on biomineralization, structure-function relations in mineralized tissues and biomimetic strategies to engineer tissue.

kozloff Prof. Ken Kozloff is an Associate Professor in Orthopaedic Surgery and Biomedical Engineering.  His research uses molecular imaging strategies and engineering tools to visualize and quantify bone cell activity and skeletal drug delivery in models of low bone mass, tissue regeneration, and altered bone mineralization dynamics. 

larkin Prof. Lisa M. Larkin is an Associate Professor in Molecular & Integrative Physiology and Biomedical Engineering.  She directs a laboratory the of Skeletal Tissue Engineering Laboratory that has developed a scaffoldless method to engineer three-dimensional muscle, nerve, tendon, bone and ligament constructs from primary, bone marrow stromal cells and adipose stem cells.  

lee Prof. Jun Hee Lee is an Assistant Professor in Molecular and Integrative Physiology and Gerontology. He studies the molecular mechanism of diverse age-associated and obesity-prompted diseases, using Drosophila and mouse models. 


Prof. Allen Liu is an Assistant Professor in Mechanical Engineering and Biomedical Engineering. His laboratory is interested in understanding the spatiotemporal dynamics of cellular processes and how defects into these processes may result in human diseases.

macdougald Prof. Ormond A. MacDougald is the John A. Faulkner Collegiate Professor of Physiology in Molecular & Integrative Physiology and Internal Medicine. He uses an interdisciplinary collaborative research approach that includes biochemistry, cell and molecular biology, transgenic animals, and human subjects to further our mechanistic understanding of adipose tissue development and metabolism.  

michele Prof. Daniel Michele is an Associate Professor in Molecular and Integrative Physiology and Internal Medicine.  His research laboratory focuses on inherited muscular dystrophies and cardiomyopathies using mouse models, cardiac and muscle physiology, and muscle cell biological approaches to probe mechanisms and develop new therapeutic approaches.  

moenter Prof. Sue Moenter is a Professor of Molecular and Integrative Physiology, Internal Medicine, and Obstetrics and Gynecology.  She co-directs of the Reproductive Sciences Program.  Her work investigates how the central nervous system regulates fertility in a variety of animal models mimicking both normal physiology and disease states such as polycystic ovary syndrome.   

noll Prof. Douglas Noll is Ann and Robert H. Lurie Professor of Biomedical Engineering, Professor of Radiology, and Co-Director of the Functional MRI Laboratory.  His laboratory is focused on magnetic resonance imaging (MRI) technology applied to a variety of application areas, but with the largest emphasis on functional brain imaging.  

pletcher Prof. Scott Pletcher is a Professor in Molecular and Integrative Physiology and a Research Professor in the Geriatrics Center.  He seeks to identify and investigate genetic and neurobiological mechanisms that are likely to be important for aging and age-related disease in humans by focusing on equivalent, conserved processes in the fruit fly, Drosophila melanogaster.   

putnam Prof. Andrew Putnam is a Professor in Biomedical Engineering whose laboratory conducts both fundamental and applied research in the broad areas of cell and tissue engineering. His fundamental biological research focuses on the interface between cells and the extracellular matrix, with a particular emphasis on the role of matrix stiffness and matrix remodeling during neovascularization. 

samuelson Prof. Linda C. Samuelson is the John A. Williams Collegiate Professor of Gastrointestinal Physiology with appointments in Molecular & Integrative Physiology and Internal Medicine.  She uses genetically engineered mouse models and human organoid cultures to study gastrointestinal function and disease, focusing on regulation of gastrointestinal stem cells.  

shikanov Prof. Ariella Shikanov is an Associate Professor Biomedical Engineering.  Using the principles of biomaterials science and tissue engineering, her lab has the goal of preserving fertility in cancer patients by creating an artificial environment that supports growth of an artificial ovary.

stegemann Prof. Jan Stegemann is a Professor of Biomedical Engineering.  His laboratory studies biomaterials and cell-matrix interactions, with a focus on how defined biomaterial microenvironments can be used to control progenitor cell function. 

wu Prof. Jun Wu is an Assistant Professor of Molecular & Integrative Physiology and a Research Assistant Professor in the Life Sciences Institute.  Her work focuses on a recently identified form of fat cells, called “beige cells”. In mice, genetic manipulations creating more of these fat cells bring strong anti-obesity and anti-diabetic effects. 

shawn-xu Prof. X.Z. Shawn Xu  is Bernard W. Agranoff Collegiate Professor in the Life Sciences and Professor of Molecular & Integrative Physiology.  He is interested in understanding some of the fundamental questions in neuroscience and physiology: how do animals detect sensory cues such as touch, light, chemicals, and temperature, how do neural circuits and synapses process sensory information to produce behavioral output, and do how genes and drugs regulate these processes? 

zhen-xu Prof. Zhen Xu is an Associate Professor in Biomedical Engineering and studies image-guided ultrasound therapy.  She is one of the primary inventors of Histotripsy, a new technology developed at the University of Michigan to precisely control acoustic cavitation for tissue fractionation and removal. 

yin Prof. Lei Yin is an Assistant Professor in Molecular & Integrative Physiology.  She utilizes an interdisciplinary research approach combining biochemistry, cellular and molecular biology, and whole-animal physiology to study the regulation and function of molecular clock systems for a better understanding pathogenesis of metabolic diseases, such as obesity, fatty liver diseases and diabetes.